Doxylamine Succinate
Doxylamine succinate is a first-generation antihistamine of the ethanolamine class. It has strong sedative and anticholinergic properties. By blocking histamine (H1) receptors and acetylcholine in the body, it effectively induces drowsiness and aids sleep onset.
Dosage by Body Weight
For adults and children 12 years of age and older, the typical dose is 25 mg taken orally once daily, 30 minutes before bedtime. Continuous use as a sleep aid should not exceed 2 weeks unless directed by a doctor. Not recommended for children under 12 years of age for insomnia.
- Body Weight
- Below 5 kg
- Dose
- Not recommended
- Frequency
- Do not administer
- Tracking Notes
- Contraindicated in infants. High risk of severe adverse effects, including respiratory depression and paradoxical excitation.
- Body Weight
- 5-7 kg
- Dose
- Not recommended
- Frequency
- Do not administer
- Tracking Notes
- Safety and efficacy have not been established for pediatric patients in this weight range.
- Body Weight
- 8-10 kg
- Dose
- Not recommended
- Frequency
- Do not administer
- Tracking Notes
- Avoid OTC administration. Use only under the direct supervision and prescription of a pediatrician.
- Body Weight
- 11-15 kg
- Dose
- Not recommended
- Frequency
- Do not administer
- Tracking Notes
- Do not use for insomnia. Only administer in pediatric combination cold medicines if specifically directed by a healthcare professional.
- Body Weight
- 16-20 kg
- Dose
- Not recommended
- Frequency
- Do not administer
- Tracking Notes
- Do not use for sleep aid purposes. Consult a physician for appropriate pediatric alternative therapies.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| Below 5 kg | Not recommended | Do not administer | Contraindicated in infants. High risk of severe adverse effects, including respiratory depression and paradoxical excitation. |
| 5-7 kg | Not recommended | Do not administer | Safety and efficacy have not been established for pediatric patients in this weight range. |
| 8-10 kg | Not recommended | Do not administer | Avoid OTC administration. Use only under the direct supervision and prescription of a pediatrician. |
| 11-15 kg | Not recommended | Do not administer | Do not use for insomnia. Only administer in pediatric combination cold medicines if specifically directed by a healthcare professional. |
| 16-20 kg | Not recommended | Do not administer | Do not use for sleep aid purposes. Consult a physician for appropriate pediatric alternative therapies. |
Formulation
Purpose
Used as a short-term sleep aid to treat occasional insomnia. It is also used in combination with other active ingredients to relieve cold and allergy symptoms, and to manage morning sickness in pregnant women.
Generic Name
Doxylamine SuccinateBranded Drug Names
Doxylamine Succinate is listed as a generic drug name. Common branded medicines that may contain the same active ingredient include:
Scheduled Drug
No. This medicine is generally not treated as a scheduled/prescription-only drug in common consumer references, but local rules may vary.